Dr. Elton Isaj Health Horizons Medicina e chirurgia oncologica

  Luo Hai Lv Qiang Wang Haichuan Research 29 November 2025 Article: 46 Read More

  Gianbattista Parlani, Giacomo Isernia, Lydia Romano, ... Piergiorgio Cao, Massimo Lenti, Gioele Simonte Published online: November 28, 2025 Read More

  Epidermal Growth Factor Receptor Exon 20 Insertion in Early Resected Non-Small Cell Lung Cancer: A Retrospective, Single-Center Study in Taiwan Read Mora

  Abstract Background:  As one of the most lethal skin cancers, melanoma has encountered many obstacles in diagnosis and therapy. Artificial Intelligence (AI) can help improve early diagnosis, prognosis, and treatment of melanoma. However, there is a lack of detailed and accurate bibliometric analysis of the field. Methods:  All publications were extracted from Web of Science Core Collection based on AI and melanoma terms. Bibliometric analysis was conducted on 1,476 articles/reviews by using VOSviewer, CiteSpace and bibliometrix for co-authorship, citation, keyword and journal analysis. Read More

 Background Operative notes from surgical procedures are essential components of patient treatment, acting as official records and facilitating communication between medical staff. However, inconsistencies in how these notes are recorded, especially in low- and middle-income countries, can jeopardize patient well-being and the smooth continuation of treatment. This research sought to assess and enhance the standard of surgical operative notes at the Ribat University Hospital, Sudan, by implementing targeted improvements. Read More

  Purpose This retrospective study aims to evaluate the efficacy and safety of unilateral biportal endoscopic discectomy (UBED) in patients with far lateral lumbar disc herniation (FLLDH). Methods A total of 25 patients with single-level FLLDH who underwent UBED between April 2023 and January 2024 were retrospectively analyzed, while 30 patients with paracentral LDH served as the control group. Primary outcomes were assessed using operation time, hospital stay, volume of drainage, complications, postoperative hospitalization duration, visual analogue scale (VAS) scores for back pain (VAS-BP) and leg pain (VAS-LP), the Oswestry Disability Index (ODI), and the modified MacNab criteria. Demographic, symptom-related, and radiographic data were also analyzed. Read More

  Background Locally advanced esophageal cancer remains a significant therapeutic challenge, with the optimal treatment strategy still debate. While previous studies suggest that concurrent chemoradiation therapy (CCRT) can improve survival, the role of esophagectomy following CCRT in patients with partial or no response has not been well-characterized, particularly in resource-limited settings. This study aimed to evaluate the survival benefit of esophagectomy following CCRT, with particular focus on non-complete responders (non-CR). Read More

  The Journal of Cardiovascular Surgery 2025 August;66(4):259-65 Patterns of visceral artery involvement and radiological malperfusion in aortic dissections Amine FIKANI *, Jerome JOUAN, Marouane BOUKHRIS, Patrick LERMUSIAUX, Antoine MILLON, Philippe TRESSON Read More

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  As robots for minimally invasive surgery (MIS) gradually become more accessible and modular, we believe there is a great opportunity to rethink and expand the visualization and control paradigms that have characterized surgical teleoperation since its inception. We conjecture that introducing one or more additional adjustable viewpoints in the abdominal cavity would not only unlock novel visualization and collaboration strategies for surgeons but also substantially boost the robustness of machine perception toward shared autonomy. Immediate advantages include controlling a second viewpoint and teleoperating surgical tools from a different perspective, which would allow collaborating surgeons to adjust their views independently and still maneuver their robotic instruments intuitively. Furthermore, we believe that capturing synchronized multi-view 3D measurements of the patient's anatomy would unlock advanced scene representations. Accurate real-time intraoperative 3D perception wi...

  Transluminal minimally invasive surgery uses natural orifices and small incisions to access internal anatomical structures, promoting quicker recovery and reduced morbidity. However, navigating instruments--catheters and endoscopes--through anatomical pathways creates frictional interactions with luminal walls, risking complications such as perforation, poor haptic feedback, and instrument buckling. In this paper, we present a new approach to actively lubricate transluminal instruments and dynamically reduce friction with surrounding tissues. This approach employs ultrasonic vibrations, at the instrument surface, to generate a pressurized fluid layer at the contact interface, lubricating the interface and thereby reducing friction. We implemented this approach in a prototype catheter, which we validated under dry and liquid-lubricated conditions, across rigid and soft interfaces, and along varied anatomical curvatures. In a cardiac catheter use case, active lubrication reduced fr...

  Advances in computer vision, particularly in optical image-based 3D reconstruction and feature matching, enable applications like marker-less surgical navigation and digitization of surgery. However, their development is hindered by a lack of suitable datasets with 3D ground truth. This work explores an approach to generating realistic and accurate ex vivo datasets tailored for 3D reconstruction and feature matching in open orthopedic surgery. A set of posed images and an accurately registered ground truth surface mesh of the scene are required to develop vision-based 3D reconstruction and matching methods suitable for surgery. We propose a framework consisting of three core steps and compare different methods for each step: 3D scanning, calibration of viewpoints for a set of high-resolution RGB images, and an optical-based method for scene registration. We evaluate each step of this framework on an ex vivo scoliosis surgery using a pig spine, conducted under real operating room ...

  Purpose: This proof-of-concept study evaluates feasibility and accuracy of an ultrasound-based navigation system for open liver surgery. Unlike most conventional systems that rely on registration to preoperative imaging, the proposed system provides navigation-guided resection using 3D models generated from intraoperative ultrasound. Methods: A pilot study was conducted in 25 patients undergoing resection of liver metastases. The first five cases served to optimize the workflow. Intraoperatively, an electromagnetic sensor compensated for organ motion, after which an ultrasound volume was acquired. Vasculature was segmented automatically and tumors semi-automatically using region-growing (n=15) or a deep learning algorithm (n=5). The resulting 3D model was visualized alongside tracked surgical instruments. Accuracy was assessed by comparing the distance between surgical clips and tumors in the navigation software with the same distance on a postoperative CT of the resected specime...